diff --git a/configure b/configure
index ca7137f341..922cd8d0ee 100755
--- a/configure
+++ b/configure
@@ -482,6 +482,7 @@ Developer options (useful when working on FFmpeg itself):
   --ignore-tests=TESTS     comma-separated list (without "fate-" prefix
                            in the name) of tests whose result is ignored
   --enable-linux-perf      enable Linux Performance Monitor API
+  --disable-large-tests    disable tests that use a large amount of memory
 
 NOTE: Object files are built at the place where configure is launched.
 EOF
@@ -1931,6 +1932,7 @@ CONFIG_LIST="
     $SUBSYSTEM_LIST
     autodetect
     fontconfig
+    large_tests
     linux_perf
     memory_poisoning
     neon_clobber_test
@@ -3724,6 +3726,7 @@ enable asm
 enable debug
 enable doc
 enable faan faandct faanidct
+enable large_tests
 enable optimizations
 enable runtime_cpudetect
 enable safe_bitstream_reader
diff --git a/tests/fate/seek.mak b/tests/fate/seek.mak
index 04f54ee6c4..284e9f3ffe 100644
--- a/tests/fate/seek.mak
+++ b/tests/fate/seek.mak
@@ -64,7 +64,6 @@ FATE_SEEK_VSYNTH_LENA-$(call ENCDEC, ASV1,          AVI)     += asv1
 FATE_SEEK_VSYNTH_LENA-$(call ENCDEC, ASV2,          AVI)     += asv2
 FATE_SEEK_VSYNTH_LENA-$(call ENCDEC, DNXHD,         DNXHD)   += dnxhd-720p
 FATE_SEEK_VSYNTH_LENA-$(call ENCDEC, DNXHD,         DNXHD)   += dnxhd-720p-rd
-FATE_SEEK_VSYNTH_LENA-$(call ENCDEC, DNXHD,         DNXHD)   += dnxhd-4k-hr-lb
 FATE_SEEK_VSYNTH_LENA-$(call ENCDEC, DNXHD,         MOV)     += dnxhd-1080i
 FATE_SEEK_VSYNTH_LENA-$(call ENCDEC, DVVIDEO,       DV)      += dv
 FATE_SEEK_VSYNTH_LENA-$(call ENCDEC, DVVIDEO,       DV)      += dv-411
@@ -80,6 +79,8 @@ FATE_SEEK_VSYNTH_LENA-$(call ENCDEC, JPEGLS,        AVI)     += jpegls
 FATE_SEEK_VSYNTH_LENA-$(call ENCDEC, LJPEG MJPEG,   AVI)     += ljpeg
 FATE_SEEK_VSYNTH_LENA-$(call ENCDEC, MJPEG,         AVI)     += mjpeg
 
+FATE_SEEK_VSYNTH_LENA-$(call ENCDEC, DNXHD,         DNXHD)-$(CONFIG_LARGE_TESTS) += dnxhd-4k-hr-lb
+
 FATE_SEEK_VSYNTH_LENA-$(call ENCDEC, MPEG1VIDEO, MPEG1VIDEO MPEGVIDEO) +=    \
                                                     mpeg1                    \
                                                     mpeg1b
@@ -158,6 +159,7 @@ fate-seek-vsynth_lena-wmv2:              SRC = fate/vsynth_lena-wmv2.avi
 fate-seek-vsynth_lena-yuv:               SRC = fate/vsynth_lena-yuv.avi
 
 FATE_SAMPLES_SEEK += $(FATE_SEEK_VSYNTH_LENA-yes:%=fate-seek-vsynth_lena-%)
+FATE_SAMPLES_SEEK += $(FATE_SEEK_VSYNTH_LENA-yes-yes:%=fate-seek-vsynth_lena-%)
 
 # files from fate-lavf
 
diff --git a/tests/fate/vcodec.mak b/tests/fate/vcodec.mak
index 452246689e..a52b93b9c2 100644
--- a/tests/fate/vcodec.mak
+++ b/tests/fate/vcodec.mak
@@ -29,13 +29,14 @@ FATE_VCODEC-$(call ENCDEC, DNXHD, DNXHD) += dnxhd-720p                  \
                                             dnxhd-720p-rd               \
                                             dnxhd-720p-10bit            \
                                             dnxhd-720p-hr-lb            \
-                                            dnxhd-4k-hr-lb              \
                                             dnxhd-uhd-hr-sq             \
                                             dnxhd-2k-hr-hq              \
                                             dnxhd-edge1-hr              \
                                             dnxhd-edge2-hr              \
                                             dnxhd-edge3-hr
 
+FATE_VCODEC-$(call ENCDEC, DNXHD, DNXHD)-$(CONFIG_LARGE_TESTS) += dnxhd-4k-hr-lb
+
 FATE_VCODEC-$(call ENCDEC, VC2 DIRAC, MOV) += vc2-420p vc2-420p10 vc2-420p12 \
                                               vc2-422p vc2-422p10 vc2-422p12 \
                                               vc2-444p vc2-444p10 vc2-444p12 \
@@ -458,7 +459,7 @@ FATE_VCODEC-$(call ENCDEC, Y41P, AVI) += y41p
 
 FATE_VCODEC-$(call ENCDEC, ZLIB, AVI) += zlib
 
-FATE_VCODEC += $(FATE_VCODEC-yes)
+FATE_VCODEC += $(FATE_VCODEC-yes) $(FATE_VCODEC-yes-yes)
 FATE_VSYNTH1 = $(FATE_VCODEC:%=fate-vsynth1-%)
 FATE_VSYNTH2 = $(FATE_VCODEC:%=fate-vsynth2-%)
 FATE_VSYNTH_LENA = $(FATE_VCODEC:%=fate-vsynth_lena-%)
